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Early Adult Reduction of Weight Through Lifestyle Intervention (EARLY) Trials

Cardiovascular disease (CVD) and its risk factors are increasing in young adults. Data from the Coronary Artery Risk Development in Young Adults (CARDIA) Study suggest that weight gain in early adulthood is associated with development of several CVD risk factors and that those with stable weight had relatively constant risk factor levels. This suggests that avoiding weight gain may reduce or prevent risk factor progression.

Successful weight loss strategies in older adults have not generally been tested in younger adults. Thus, the National Heart, Lung, and Blood Institute (NHLBI) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) of the National Institutes of Health (NIH) are funding seven cooperative agreements to conduct clinical research studies to develop, refine, and test innovative behavioral and/or environmental approaches for weight control in young adults at high risk for weight gain. Seven randomized clinical trials of innovative behavioral approaches for weight control in young adults are included in the Early Adult Reduction of weight change through LifestYle Intervention (EARLY) program.